Members of this working group are interested in enactments and contestations of universality within and through the sciences in a post-colonial world. We train our analysis on universality in science as an ideology, an aspiration, and a social fact. How does science count as science, and which science counts? We attend to the critique of science – for example through decolonizing and feminist approaches – and also to science as critique. We begin by engaging with the ways in which science as a form of knowledge and practice becomes crucial for (re)imagining and producing lives and worlds in specific socio-political contexts. By following the work of scientists from fields as varied as astronomy, psychiatry, genetics, field biology, and artificial intelligence, we investigate processes of localization as well as various forms of political mobilization with, for, and against science. In analysing the universality of science, we aim to explore the possibilities of “critique” in and of the sciences today. While our focus is on the natural sciences, our discussion may lead us to break open the dichotomy of the sciences and humanities, also by reflecting on our own situated positionalities.